Transcription profiling of mouse masticatory and limb skeletal muscle

ABSTRACT: Distinctions between craniofacial and axial muscles exist from the onset of development and throughout adulthood. The masticatory muscles are a specialized group of craniofacial muscles that retain embryonic fiber properties throughout adulthood, suggesting that the developmental origin of these muscles may govern a pattern of expression that differs from limb muscles. To determine the extent of these differences, expression profiling of total RNA isolated from the masseter and tibialis anterior (TA) muscles of adult female mice was performed, which identified transcriptional changes in unanticipated functional classes of genes in addition to those associated with fiber type. In particular, the masseters displayed a reduction of transcripts associated with load-sensing and anabolic process

ORGANISM(S): Mus musculus

SUBMITTER: Elisabeth Barton 

PROVIDER: E-GEOD-11114 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress