Gene expression analysis in polytrauma patients comparing sepsis vs. non-sepsis

ABSTRACT: BACKGROUND: Despite best supportive intensive care, the development of severe sepsis and septic shock after trauma is still associated with a high mortality rate in intensive care units (ICU). Incomplete knowledge of the pathophysiological and biochemical mechanisms that lead to perturbations of the host system is a major cause for this clinical entity. This lack of knowledge is mirrored in a delay in both diagnosis of sepsis and stratification of patients at risk. The current diagnostic and classification methods do not provide an early and reliable evidence for the development of sepsis and consequently lead to uncertainty in the classification and a delay in the initiation of an adequate therapy. Here, we present a prospective study performed with a well-defined patient cohort suffering

ORGANISM(S): Homo sapiens

SUBMITTER: Hamid Hossain 

PROVIDER: E-GEOD-12624 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress