Platelet Activating Factor Receptor and Innate Immunity

ABSTRACT: This data series contains spotted oligo microarray data from 10 different experiments using Agilent Rat v2 microarrays. This data is being made public in support of Fillon S et al. Journal of Immunology, (2006). Proinflammatory bacterial components are at least partially responsible for causing the clinical features of sepsis, a syndrome that causes >100,000 deaths each year in the US (1). In the case of Gram positive infection, a key bacterial element recognized by the innate immune system is the cell wall, a complex network of peptidoglycan covalently linked to teichoic acids, proteins and lipoproteins. The current model of innate immune recognition of Gram positive bacteria suggests bacterial cell wall interacts with host recognition proteins, such as toll-like receptors (TLR) and Nod p

ORGANISM(S): Rattus norvegicus

SUBMITTER: Elaine Tuomanen 

PROVIDER: E-GEOD-5545 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress