Transcription profiling of human fibrosarcoma cells to study the relative contributions of Jak1 and Jak2 in IFNg signaling

ABSTRACT: General impact of Jak1 and Jak2 inhibition on IFNg-mediated target gene expression. U4C-Jak1AS and g2A-Jak2AS cells were stimulated with IFNg and treated with either 1NM-PP1 (to inhibit the activity only of the analog-sensitive mutant) or JI1 (to suppress both wild-type and analog-sensitive Jaks) for 24h.

ORGANISM(S): Homo sapiens

SUBMITTER: Arnaud Muller 

PROVIDER: E-MEXP-2621 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress