The role of insulin resistance in experimental diabetic retinopathy - genetic and molecular aspects

ABSTRACT: Patients with long-duration diabetes develop cardiovascular complications resulting in highly increased mortality and complications which affect the kidneys, eyes and peripheral nerves associated with high morbidity. Among the diabetic complications, damage in the eye, diabetic retinopathy, is the most common microvascular complication of diabetes. Diabetic retinopathy is a leading cause of vision-loss globally. It is characterized by a number of different patho-mechanisms including changes in vascular permeability, capillary degeneration, and finally at a late stage overshooting formation of new blood vessels. This expression analysis focused on the use of different experimental models for Diabetes Mellitus and its complications (for a review see 1: Al-Awar et al: Experimental Diabetes

ORGANISM(S): Rattus norvegicus

SUBMITTER: Andreas Herling 

PROVIDER: E-MTAB-5563 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress