Elevated levels of interleukin-33 are associated with asthma: A meta-analysis.

ABSTRACT:

Background

Previous studies reported that patients with asthma showed higher levels of interleukin (IL)-33 in peripheral blood, compared to healthy control (HCs). However, we also noticed that there were no significant differences of IL-33 levels between controls and asthma patients in a recent study. We aim to conduct this meta-analysis and evaluate the feasibility of IL-33 in peripheral blood that may act as a promising biomarker in asthma.

Methods

Articles published before December 2022 were searched in these databases (PubMed, Web of Science, EMBASE, and Google Scholar). We used STATA 12.0 software to compute the results.

Results

The study showed that asthmatics showed higher IL-33 level in serum and plasma, compared to HCs (serum: standard mean difference [SMD] 2

SUBMITTER: Zhao R 

PROVIDER: S-EPMC10116908 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature