Perifocal Zone of Brain Gliomas: Application of Diffusion Kurtosis and Perfusion MRI Values for Tumor Invasion Border Determination

ABSTRACT:

Simple Summary

Preoperative determination of glioma invasion borders remains crucial for neuroradiology. Diffusion kurtosis imaging (DKI) is one of the promising tools as it reflects complex tissue microstructure. Pseudo-continuous arterial spin labeling (pCASL) perfusion is a reliable method to distinguish the most malignant tumor part. In 50 high-grade glioma patients, we demonstrated significant differences between the DKI values in peritumoral white matter (normal-appearing on conventional MRI) and unaffected contralateral hemisphere white matter, which may indicate possible infiltration of normal-appearing peritumoral white matter by glioma cells. The study demonstrated the presence of tumor cells within the edema zone in all gliomas. Tumor cells and tumor stem-like cells wer

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PROVIDER: S-EPMC10216555 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature