Brain injury in preterm infants with surgical necrotizing enterocolitis: clinical and bowel pathological correlates.

ABSTRACT:

Background

The objective of this study was to determine the risk factors and outcomes of white matter brain injury (WMBI) on magnetic resonance imaging (MRI) at term-equivalent age in infants with surgical necrotizing enterocolitis (NEC).

Methods

This retrospective study compared clinical/pathological information between infants with and those without WMBI.

Results

Out of 69 infants with surgical NEC, 17 (24.6%) had mild WMBI, 13 (18.8%) had moderate WMBI, and six (8.7%) had severe WMBI on the brain MRI. Several clinical factors (gestational age, more red blood cell (RBC) transfusions before NEC onset, pneumoperitoneum, earlier NEC onset age, postoperative ileus, acute kidney injury (AKI) by serum creatinine, postnatal steroids, hospital stay) and histopathological fi

SUBMITTER: Garg PM 

PROVIDER: S-EPMC10308193 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature