General and Specific Factors of Environmental Stress and Their Associations With Brain Structure and Dimensions of Psychopathology.

ABSTRACT:

Background

Early-life stressors can adversely affect the developing brain. While hierarchical modeling has established the existence of a general factor of psychopathology, no studies have modeled a general factor of environmental stress and related this factor to brain development. Using a large sample of children from the ABCD (Adolescent Brain Cognitive Development) Study, the current study aimed to identify general and specific factors of environmental stress and test their associations with brain structure and psychopathology.

Methods

In a sample of 11,878 children, bifactor modeling and higher-order (second-order) modeling identified general and specific factors of environmental stress: family dynamics, interpersonal support, neighborhood socioeconomic status deprivati

SUBMITTER: Jeong HJ 

PROVIDER: S-EPMC10382692 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature