Association of cerebellar volume with cognitive and motor function in adults with congenital heart disease.

ABSTRACT:

Introduction

Patients with congenital heart disease (CHD) are at risk for cognitive and motor function impairments, brain injury, and smaller total brain volumes. The specific vulnerability of the cerebellum and its role in cognitive and motor functions in adults with congenital heart disease is not well defined.

Methods

Forty-three patients with CHD and 53 controls between 18 and 32 years underwent brain magnetic resonance imaging and cognitive, executive (EF), and motor function assessment. Cerebellar volumes were obtained using EasyMeasure and SUIT Toolbox. Associations between cerebellar volumes and cognitive and motor function were calculated using linear models.

Results

General cognitive and pure motor functions were lower in patients compared to controls (P < 0

SUBMITTER: Naef N 

PROVIDER: S-EPMC10570150 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature