Ontology highlight
ABSTRACT:
SUBMITTER: Padrela BE
PROVIDER: S-EPMC10581242 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Padrela Beatriz E BE Lorenzini Luigi L Collij Lyduine E LE García David Vállez DV Coomans Emma E Ingala Silvia S Tomassen Jori J Deckers Quinten Q Shekari Mahnaz M Geus Eco Jc de EJ van de Giessen Elsmarieke E Kate Mara Ten MT Visser Pieter Jelle PJ Barkhof Frederik F Petr Jan J Braber Anouk den AD Mutsaerts Henk Jmm HJ
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20230526 10
Aging-related cognitive decline can be accelerated by a combination of genetic factors, cardiovascular and cerebrovascular dysfunction, and amyloid-β burden. Whereas cerebral blood flow (CBF) has been studied as a potential early biomarker of cognitive decline, its normal variability in healthy elderly is less known. In this study, we investigated the contribution of genetic, vascular, and amyloid-β components of CBF in a cognitively unimpaired (CU) population of monozygotic older twins. We incl ...[more]