Presumed Muller Cell Activation in Multiple Evanescent White Dot Syndrome.

ABSTRACT:

Purpose

The purpose of this study was to investigate the foveal changes occurring in multiple evanescent white dot syndrome (MEWDS) using multimodal imaging techniques with a specific focus on hyper-reflective dots (HRDs).

Methods

This was a retro-prospective observational study including 35 eyes with active MEWDS. Structural and en face optical coherence tomography (OCT) was performed, with follow-up visits at 2 weeks, 6 weeks, and 2 months from baseline. HRD percentage area (HRD % area) was calculated in a 600 µm fovea centered circle on en face OCT, after background subtraction and image binarization. HRD % area was compared with 23 fellow control eyes. Longitudinal changes in the HRD % areas were assessed using repeated-measure statistics.

Results

HRDs were observ

SUBMITTER: Cicinelli MV 

PROVIDER: S-EPMC10587856 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature