Associations Between Polygenic Scores for Cognitive and Non-cognitive Factors of Educational Attainment and Measures of Behavior, Psychopathology, and Neuroimaging in the Adolescent Brain Cognitive Development Study.

ABSTRACT:

Background

Both cognitive and non-cognitive (e.g., traits like curiosity) factors are critical for social and emotional functioning and independently predict educational attainment. These factors are heritable and genetically correlated with a range of health-relevant traits and behaviors in adulthood (e.g., risk-taking, psychopathology). However, whether these associations are present during adolescence, and to what extent these relationships diverge, could have implications for adolescent health and well-being.

Methods

Using data from 5,517 youth of European ancestry from the ongoing Adolescent Brain Cognitive Development^SM Study, we examined associations between polygenic scores (PGS) for cognitive and non-cognitive factors and outcomes related to cognition, so

SUBMITTER: Gorelik AJ 

PROVIDER: S-EPMC10635216 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature