Association of serum leptin and ghrelin levels with smoking status on body weight: a systematic review and meta-analysis.

ABSTRACT:

Background and aims

Smoking cigarettes is a major global health problem that affects appetite and weight. The aim of this systematic review was to determine how smoking affected plasma leptin and ghrelin levels.

Methods

A comprehensive search of PubMed, Scopus, Web of Science, and Ovid was conducted using a well-established methodology to gather all related publications.

Results

A total of 40 studies were included in the analysis of 11,336 patients. The overall effect showed a with a mean difference (MD) of -1.92[95%CI; -2.63: -1.20] and p = 0.00001. Subgroup analysis by study design revealed significant differences as well, but with high heterogeneity within the subgroups (I² of 82.3%). Subgroup by sex showed that there was a significant diff

SUBMITTER: Shaheen N 

PROVIDER: S-EPMC10725976 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature