Lipid profile of circulating placental extracellular vesicles during pregnancy identifies foetal growth restriction risk.
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ABSTRACT:
SUBMITTER: Klemetti MM
PROVIDER: S-EPMC10865917 | biostudies-literature | 2024 Feb
REPOSITORIES: biostudies-literature
Publications
Lipid profile of circulating placental extracellular vesicles during pregnancy identifies foetal growth restriction risk.
Klemetti Miira M MM Pettersson Ante B V ABV Ahmad Khan Aafaque A Ermini Leonardo L Porter Tyler R TR Litvack Michael L ML Alahari Sruthi S Zamudio Stacy S Illsley Nicholas P NP Röst Hannes H Post Martin M Caniggia Isabella I
Journal of extracellular vesicles 20240201 2
Small-for-gestational age (SGA) neonates exhibit increased perinatal morbidity and mortality, and a greater risk of developing chronic diseases in adulthood. Currently, no effective maternal blood-based screening methods for determining SGA risk are available. We used a high-resolution MS/MS<sup>ALL</sup> shotgun lipidomic approach to explore the lipid profiles of small extracellular vesicles (sEV) released from the placenta into the circulation of pregnant individuals. Samples were acquired fro ...[more]
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