Cerebral pulsatility in relation with various imaging markers of cerebral small vessel disease: a longitudinal community-based study.

ABSTRACT:

Background

Cerebral pulsatility is thought to reflect arterial stiffness and downstream microvascular resistance. Although previous studies indicated cerebral pulsatility might closely relate to development of cerebral small vessel disease (SVD), yet evidence remain controversial and longitudinal data are rare.

Objective

We aimed to explore relationships of cerebral pulsatility with severity and progression of various SVD imaging markers among the community-dwelling elderly.

Design

A longitudinal cohort study.

Methods

As part of the prospective community-based Shanghai Aging Study cohort, dementia- and stroke-free elderly were recruited for baseline assessment of cerebral pulsatility and SVD severity during 2010-2011 and traced for SVD progression during 2016-2

SUBMITTER: Zhong W 

PROVIDER: S-EPMC10874147 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature