Assessment tools for cognitive performance in Parkinson's disease and its genetic contributors.

ABSTRACT:

Background

We have shown that genetic factors associating with motor progression of Parkinson's disease (PD), but their roles in cognitive function is poorly understood. One reason is that while cognitive performance in PD can be evaluated by various cognitive scales, there is no definitive guide indicating which tool performs better.

Methods

Data were obtained from the Parkinson's Progression Markers Initiative, where cognitive performance was assessed using five cognitive screening tools, including Symbol Digit Modalities Test (SDMT), Montreal Cognitive Assessment, Benton Judgment of Line Orientation, Modified Semantic Fluency Test, and Letter Number Sequencing Test, at baseline and subsequent annual follow-up visit for 5 years. Genetic data including ApoE and other

SUBMITTER: Cao LX 

PROVIDER: S-EPMC11233456 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature