Melanoma-specific survival of patients with uveal melanoma and liver metastases diagnosed between 2005 and 2021.

ABSTRACT:

Background

Uveal melanoma is the most common malignant tumor of the eye in adults. About half of the patients develop distant metastases, most commonly liver metastases (>90%). These are associated with poorer overall survival compared to patients with extrahepatic metastases.

Patients and methods

In this retrospective study, patients diagnosed with metastatic uveal melanoma between January 2005 and December 2021 and treated at the Center for Dermato-oncology at the University of Tübingen, were included. The total cohort was divided into two groups. Group 1, in which the first diagnosis of metastasis was between 2005 and 2015 and group 2 with first metastasis between 2016 and 2021. Melanoma-specific survival (MSS) and progression-free survival (PFS) were calculated with the

SUBMITTER: Wiens L 

PROVIDER: S-EPMC11342429 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature