Decaffeinated coffee and glucose metabolism in young men.
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ABSTRACT: Objective
The epidemiological association between coffee drinking and decreased risk of type 2 diabetes is strong. However, caffeinated coffee acutely impairs glucose metabolism. We assessed acute effects of decaffeinated coffee on glucose and insulin levels.Research design and methods
This was a randomized, cross-over, placebo-controlled trial of the effects of decaffeinated coffee, caffeinated coffee, and caffeine on glucose, insulin, and glucose-dependent insulinotropic polypeptide (GIP) levels during a 2-h oral glucose tolerance test (OGTT) in 11 young men.Results
Within the first hour of the OGTT, glucose and insulin were higher for decaffeinated coffee than for placebo (P < 0.05). During the whole OGTT, decaffeinated coffee yielded higher insulin than placebo and lower glucose and a higher insulin sensitivity index than caffeine. Changes in GIP could not explain any beverage effects on glucose and insulin.Conclusions
Some types of decaffeinated coffee may acutely impair glucose metabolism but less than caffeine.
SUBMITTER: Greenberg JA
PROVIDER: S-EPMC2809264 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Publications
Decaffeinated coffee and glucose metabolism in young men.
Greenberg James A JA Owen David R DR Geliebter Allan A
Diabetes care 20091116 2
<h4>Objective</h4>The epidemiological association between coffee drinking and decreased risk of type 2 diabetes is strong. However, caffeinated coffee acutely impairs glucose metabolism. We assessed acute effects of decaffeinated coffee on glucose and insulin levels.<h4>Research design and methods</h4>This was a randomized, cross-over, placebo-controlled trial of the effects of decaffeinated coffee, caffeinated coffee, and caffeine on glucose, insulin, and glucose-dependent insulinotropic polype ...[more]
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