Adolescent body mass index and erythrocyte sedimentation rate in relation to colorectal cancer risk.

ABSTRACT:

Objective

Adult obesity and inflammation have been associated with risk of colorectal cancer (CRC); however, less is known about how adolescent body mass index (BMI) and inflammation, as measured by erythrocyte sedimentation rate (ESR), relate to CRC risk. We sought to evaluate these associations in a cohort of 239 658 Swedish men who underwent compulsory military enlistment examinations in late adolescence (ages 16-20 years).

Design

At the time of the conscription assessment (1969-1976), height and weight were measured and ESR was assayed. By linkage to the national cancer registry, these conscripts were followed for CRC through 1 January 2010. Over an average of 35 years of follow-up, 885 cases of CRC occurred, including 501 colon cancers and 384 rectal cancers. Cox regres

SUBMITTER: Kantor ED 

PROVIDER: S-EPMC4674372 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature