Longitudinal sleep phenotypes among offspring of bipolar parents and community controls.

ABSTRACT:

Background

Sleep disturbances are a prominent feature of bipolar disorder (BP). However, it remains unclear how sleep phenotypes may evolve among at-risk youth, and their relevance to BP onset.

Methods

Pittsburgh Bipolar Offspring Study (BIOS) offspring (ages 10-18) and their parents completed assessments approximately every two years pertaining to current psychopathology and offspring sleep habits. A latent transition analysis (LTA) identified latent sleep groups within offspring based on their ratings of six sleep domains using the School Sleep Habits Survey. Demographic and clinical characteristics were compared between sleep groups. Logistic regression tested links between sleep group and BP onset at the subsequent assessment.

Results

The LTA model identified late

SUBMITTER: Levenson JC 

PROVIDER: S-EPMC5500225 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature