Serum C-peptide concentration and prostate cancer: A meta-analysis of observational studies.

ABSTRACT:

Background

The association between serum C-peptide concentration and prostate cancer remains unexplored. Therefore, we conducted a meta-analysis to assess whether C-peptide serum concentrations are associated with increased prostate cancer risk.

Methods

Several databases were searched to identify relevant original research articles published before November 2017. Random-effects models were used to summarize the overall estimate of the multivariable-adjusted odds ratios (ORs) with 95% confidence intervals (CIs).

Results

Nine observational studies involving 11,796 participants were identified. The findings of the meta-analysis indicated that the association between serum C-peptide concentration and prostate cancer was not significant (OR: 1.15, 95% CI: 0.85-1.54; for hi

SUBMITTER: Guo ZL 

PROVIDER: S-EPMC6081093 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature