Association of Delirium Response and Safety of Pharmacological Interventions for the Management and Prevention of Delirium: A Network Meta-analysis.

ABSTRACT:

Importance

Although several pharmacological interventions for delirium have been investigated, their overall benefit and safety remain unclear.

Objective

To evaluate evidence regarding pharmacological interventions for delirium treatment and prevention.

Data sources

PubMed, Embase, ProQuest, ScienceDirect, Cochrane Central, Web of Science, ClinicalKey, and ClinicalTrials.gov from inception to May 17, 2018.

Study selection

Randomized clinical trials (RCTs) examining pharmacological interventions for delirium treatment and prevention.

Data extraction and synthesis

To extract data according to a predetermined list of interests, the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines were applied, and all meta-analytic proc

SUBMITTER: Wu YC 

PROVIDER: S-EPMC6495351 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature