¹⁸F-Fluoromethylcholine-positron emission tomography/computed tomography for diagnosing bone and lymph node metastases in patients with intermediate- or high-risk prostate cancer.

ABSTRACT:

Background

The use of molecular imaging in staging of prostate cancer (PC) is debated. In patients with newly diagnosed PC we investigated the diagnostic value of ¹⁸F-flouromethylcholine positron emission tomography/computed tomography (¹⁸F-FCH-PET/CT) for the detection of bone and lymph node metastases compared to whole-body bone scintigraphy (WBS) with technetium-99-methylene diphosphonate (^99mTc-MDP) and results of extended pelvic lymph node dissection, respectively.

Materials and methods

Between January 2013 and April 2016, 143 patients, aged 49-83, mean 69, years with newly diagnosed PC and disease characteristics necessitating WBS underwent both WBS and ¹⁸F-FCH-PET/CT using magnetic resonance imaging as standard. Eighty of th

SUBMITTER: Mortensen MA 

PROVIDER: S-EPMC6713799 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature