Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy.
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ABSTRACT:
SUBMITTER: Gauthreaux K
PROVIDER: S-EPMC7160616 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy.
Gauthreaux Kathryn K Bonnett Tyler A TA Besser Lilah M LM Brenowitz Willa D WD Teylan Merilee M Mock Charles C Chen Yen-Chi YC Chan Kwun C G KCG Keene C Dirk CD Zhou Xiao-Hua XH Kukull Walter A WA
Journal of neuropathology and experimental neurology 20200501 5
It remains unclear what clinical features inform the accuracy of a clinical diagnosis of Alzheimer disease (AD). Data were obtained from the National Alzheimer's Coordinating Center to compare clinical and neuropathologic features among participants who did or did not have Alzheimer disease neuropathologic changes (ADNC) at autopsy. Participants (1854) had a clinical Alzheimer dementia diagnosis and ADNC at autopsy (Confirmed-AD), 204 participants had an AD diagnosis and no ADNC (AD-Mimics), and ...[more]
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