Early-Life Environmental Exposures and Childhood Obesity: An Exposome-Wide Approach.

ABSTRACT:

Background

Chemical and nonchemical environmental exposures are increasingly suspected to influence the development of obesity, especially during early life, but studies mostly consider single exposure groups.

Objectives

Our study aimed to systematically assess the association between a wide array of early-life environmental exposures and childhood obesity, using an exposome-wide approach.

Methods

The HELIX (Human Early Life Exposome) study measured child body mass index (BMI), waist circumference, skinfold thickness, and body fat mass in 1,301 children from six European birth cohorts age 6-11 y. We estimated 77 prenatal exposures and 96 childhood exposures (cross-sectionally), including indoor and outdoor air pollutants, built environment, green spaces, tobacco smoki

SUBMITTER: Vrijheid M 

PROVIDER: S-EPMC7313401 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature