Prognostic and clinicopathological significance of systemic immune-inflammation index in colorectal cancer: a meta-analysis.

ABSTRACT:

Background

Previous studies on the systemic immune-inflammation index (SII), which is based on platelet, neutrophil and lymphocyte counts, as a prognostic marker in patients with colorectal cancer (CRC) yielded inconsistent results. The aim of this study was to evaluate the prognostic and clinicopathological role of SII in CRC via meta-analysis.

Methods

A comprehensive literature survey was performed on PubMed, Web of Science, Embase and the Cochrane Library databases to include studies published up to 6 April 2020. Pooled hazard ratios (HRs) and odds ratios (ORs) with 95% confidence intervals (CIs) were computed to estimate the prognostic and clinicopathological value of SII in CRC.

Results

A total of 12 studies published between 2016 and 2019 were included in

SUBMITTER: Dong M 

PROVIDER: S-EPMC7357045 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature