Cardiac Troponin I and Incident Stroke in European Cohorts: Insights From the BiomarCaRE Project.

ABSTRACT:

Background and purpose

Stroke is a common cause of death and a leading cause of disability and morbidity. Stroke risk assessment remains a challenge, but circulating biomarkers may improve risk prediction. Controversial evidence is available on the predictive ability of troponin concentrations and the risk of stroke in the community. Furthermore, reports on the predictive value of troponin concentrations for different stroke subtypes are scarce.

Methods

High-sensitivity cardiac troponin I (hsTnI) concentrations were assessed in 82 881 individuals (median age, 50.7 years; 49.7% men) free of stroke or myocardial infarction at baseline from 9 prospective European community cohorts. We used Cox proportional hazards regression to determine relative risks, followed by measures of

SUBMITTER: Camen S 

PROVIDER: S-EPMC7447179 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature