Increased integration between default mode and task-relevant networks in children with ADHD is associated with impaired response control.

ABSTRACT: Default mode network (DMN) dysfunction is theorized to play a role in attention lapses and task errors in children with attention-deficit/hyperactivity disorder (ADHD). In ADHD, the DMN is hyperconnected to task-relevant networks, and both increased functional connectivity and reduced activation are related to poor task performance. The current study extends existing literature by considering interactions between the DMN and task-relevant networks from a brain network perspective and by assessing how these interactions relate to response control. We characterized both static and time-varying functional brain network organization during the resting state in 43 children with ADHD and 43 age-matched typically developing (TD) children. We then related aspects of network integration to go/no-go

SUBMITTER: Duffy KA 

PROVIDER: S-EPMC8278154 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature