The effects of signalment, diet, geographic location, season, and colitis associated with antimicrobial use or Salmonella infection on the fecal microbiome of horses.

ABSTRACT:

Background

The fecal microbiome of healthy horses may be influenced by signalment, diet, environmental factors, and disease.

Objectives

To assess the effects of age, breed, sex, geographic location, season, diet, and colitis caused by antibiotic use (antimicrobial-associated diarrhea [AAD]) and Salmonella infection on fecal microbiota.

Animals

Healthy horses (n = 80) were sampled from nonhospital environments across multiple geographical locations in the United States. Horses with AAD (n = 14) were defined as those that developed diarrhea secondary to antimicrobial use. Horses with Salmonella infection (n = 12) were presented with spontaneous onset of colitis and subsequently tested positive on Salmonella quantitative polymerase chain reaction. All horses were >1 year

SUBMITTER: Arnold CE 

PROVIDER: S-EPMC8478058 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature