Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy.
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ABSTRACT:
SUBMITTER: Nakayama M
PROVIDER: S-EPMC8626564 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Publications
Image contrast assessment of metal-based nanoparticles as applications for image-guided radiation therapy.
Nakayama Masao M Akasaka Hiroaki H Miyazaki Eiichi E Goto Yoshihiro Y Oki Yuya Y Kawate Yosuke Y Morita Kenta K Sasaki Ryohei R
Physics and imaging in radiation oncology 20211001
Metal-based nanoparticles (NPs) have been extensively studied for dose enhancement applications in radiation therapy. This study investigated the utility of such NPs for image-guided radiation therapy (IGRT). Phantom images of gold NPs (AuNPs) and titanium peroxide NPs (TiOxNPs) with different concentrations were acquired using IGRT modalities, including cone-beam computed tomography (CBCT). AuNPs induced strong contrast enhancement in kV energy CBCT images, whereas TiOxNPs at high concentration ...[more]
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