Modeling temporal and hormonal regulation of plant transcriptional response to wounding.

ABSTRACT: Plants respond to wounding stress by changing gene expression patterns and inducing the production of hormones including jasmonic acid. This wounding transcriptional response activates specialized metabolism pathways such as the glucosinolate pathways in Arabidopsis thaliana. While the regulatory factors and sequences controlling a subset of wound-response genes are known, it remains unclear how wound response is regulated globally. Here, we how these responses are regulated by incorporating putative cis-regulatory elements, known transcription factor binding sites, in vitro DNA affinity purification sequencing, and DNase I hypersensitive sites to predict genes with different wound-response patterns using machine learning. We observed that regulatory sites and regions of open chromatin dif

SUBMITTER: Moore BM 

PROVIDER: S-EPMC8824630 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature