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Prevalence of Frailty and Associations with Oral Anticoagulant Prescribing in Atrial Fibrillation.


ABSTRACT:

Background

Frailty is often cited as a factor influencing oral anticoagulation (OAC) prescription in patients with non-valvular atrial fibrillation (NVAF). We sought to determine the prevalence of frailty and its association with OAC prescription in older veterans with NVAF.

Methods

We used ICD-9 codes in Veterans Affairs (VA) records and Medicare claims data to identify patients with NVAF and CHA2DS2VASC ≥2 receiving care between February 2010 and September 2015. We examined rates of OAC prescription, further stratified by direct oral anticoagulant (DOAC) or vitamin K antagonist (VKA). Participants were characterized into 3 categories: non-frail, pre-frail, and frail based on a validated 30-item EHR-derived frailty index. We examined relations between

SUBMITTER: Sanghai SR 

PROVIDER: S-EPMC8904680 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature