Electrogenerated chemiluminescence of a Ru(bpy)₃ ²⁺/arginine system: a specific and sensitive detection of acetaminophen.

ABSTRACT: Ru(bpy)₃Cl₂/TPrA is a prominent and widely used ECL system in analytical science. However, the co-reactant TPrA restricts the variety of applications because of its toxicity, volatility, and high cost. Here, we use arginine (Arg) as an alternative co-reactant for Ru(bpy)₃ ²⁺ by taking advantage of its low cost, non-toxicity, and biocompatibility. The mechanism of the Ru(bpy)₃ ²⁺/Arg system is that the deprotonated Arg can react with Ru(bpy)₃ ²⁺ to release emission. The similarity between the Ru(bpy)₃ ²⁺/Arg, Ru(bpy)₃ ²⁺/TPrA, and Ru(bpy)₃ ²⁺/DBAE systems demonstrates that Arg can be used as an alternative co-reactant for Ru(bpy)₃

SUBMITTER: Xiao Y 

PROVIDER: S-EPMC8979285 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature