Novel Bacteriophage Specific against Staphylococcus epidermidis and with Antibiofilm Activity.

ABSTRACT: Staphylococcus epidermidis has emerged as the most important pathogen in infections related to indwelling medical devices, and although these infections are not life-threatening, their frequency and the fact that they are extremely difficult to treat represent a serious burden on the public health system. Treatment is complicated by specific antibiotic resistance genes and the formation of biofilms. Hence, novel therapeutic strategies are needed to fight these infections. A novel bacteriophage CUB-EPI_14 specific to the bacterial species S. epidermidis was isolated from sewage and characterized genomically and phenotypically. Its genome contains a total of 46,098 bp and 63 predicted genes, among which some have been associated with packaging and lysis-associated proteins, str

SUBMITTER: Fanaei Pirlar R 

PROVIDER: S-EPMC9230115 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature