Diagnostic Accuracy of 2-[¹⁸F]FDG-PET and whole-body DW-MRI for the detection of bone marrow metastases in children and young adults.

ABSTRACT:

Objectives

To compare the diagnostic accuracy of 2-[¹⁸F]fluoro-2-deoxy-D-glucose-enhanced positron emission tomography (2-[¹⁸F]FDG-PET) and diffusion-weighted magnetic resonance imaging (DW-MRI) for the detection of bone marrow metastases in children and young adults with solid malignancies.

Methods

In this cross-sectional single-center institutional review board-approved study, we investigated twenty-three children and young adults (mean age, 16.8 years ± 5.1 [standard deviation]; age range, 7-25 years; 16 males, 7 females) with 925 bone marrow metastases who underwent 66 simultaneous 2-[¹⁸F]FDG-PET and DW-MRI scans including 23 baseline scans and 43 follow-up scans after chemotherapy between May 2015 and July 2020. Four reviewers evaluated

SUBMITTER: Rashidi A 

PROVIDER: S-EPMC9232918 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature