Quantitative susceptibility mapping as a measure of cerebral oxygenation in neonatal piglets.

ABSTRACT: Prominence of cerebral veins using susceptibility weighted magnetic resonance imaging (SWI) has been used as a qualitative indicator of cerebral venous oxygenation (CvO₂). Quantitative susceptibility mapping (QSM) adds more precision to the assessment of CvO₂, but has not been applied to neonatal hypoxic ischemic injury (HII). We proposed to study QSM measures of venous susceptibility and their correlation with direct measures of brain oxygenation and cerebral blood flow (CBF) in the neonatal piglet. The association of QSM intravascular cerebral venous susceptibility, with brain tissue O₂ tension, CBF, cortical tissue oxyhemoglobin saturation, and the partial pressure of oxygen in arterial blood measurement during various oxygenation states wa

SUBMITTER: Bartnik-Olson BL 

PROVIDER: S-EPMC9254037 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature