Association of Barrett's esophagus with Helicobacter pylori infection: a meta-analysis.

ABSTRACT:

Background and aims

Barrett's esophagus (BE) is the only recognized precursor for esophageal adenocarcinoma. Helicobacter pylori (H. pylori) infection is a major contributing factor towards upper gastrointestinal diseases, but its relationship with BE remains controversial. Some previous studies suggested that H. pylori infection negatively correlated with BE, while others did not. This may be attributed to the difference in the selection of control groups among studies. The present meta-analysis aims to clarify their association by combining all available data from well-designed studies.

Methods

The PubMed, EMBASE, and Cochrane Library databases were searched. Odds ratios (ORs) with 95% confidence intervals (CIs) were pooled by a ra

SUBMITTER: Ma S 

PROVIDER: S-EPMC9403448 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature