Tea consumption and risk of lower respiratory tract infections: a two-sample mendelian randomization study.

ABSTRACT:

Background

Observational studies have reported the association between tea consumption and the risk of lower respiratory tract infections (LRTIs). However, a consensus has yet to be reached, and whether the observed association is driven by confounding factors or reverse causality remains unclear.

Method

A two-sample Mendelian randomization (MR) analysis was conducted to determine whether genetically predicted tea intake is causally associated with the risk of common LRTI subtypes. Genome-wide association study (GWAS) from UK Biobank was used to identify single-nucleotide polymorphisms (SNPs) associated with an extra cup of tea intake each day. The summary statistics for acute bronchitis, acute bronchiolitis, bronchiectasis, pneumonia, and influenza and pneumonia were derive

SUBMITTER: Chen Y 

PROVIDER: S-EPMC9427168 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature