A Plasmid Carrying bla_IMP-56 in Pseudomonas aeruginosa Belonging to a Novel Resistance Plasmid Family.

ABSTRACT: bla_IMP and bla_VIM are the most detected plasmid-encoded carbapenemase genes in Pseudomonas aeruginosa. Previous studies have reported plasmid sequences carrying bla_IMP variants, except bla_IMP-56. In this study, we aimed to characterize a plasmid carrying bla_IMP-56 in a P. aeruginosa strain isolated from a Mexican hospital. The whole genome of P. aeruginosa strain PE52 was sequenced using Illumina Miseq 2 × 150 bp, with 5 million paired-end reads. We characterized a 27 kb plasmid (pPE52IMP) that carried bla_IMP-56. The phylogenetic analysis of RepA in pPE52IMP and 33 P. aeruginosa plasmids carrying resistance genes reported in the GenBank revealed that pPE52

SUBMITTER: Gomez-Martinez J 

PROVIDER: S-EPMC9501424 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature