Establishment and validation of individualized clinical prognostic markers for LUAD patients based on autophagy-related genes.
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ABSTRACT:
SUBMITTER: Fei Y
PROVIDER: S-EPMC9550247 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
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Establishment and validation of individualized clinical prognostic markers for LUAD patients based on autophagy-related genes.
Fei Yuchang Y Xu Junyi J Ge Liping L Chen Luting L Yu Huan H Pan Lei L Chen Peifeng P
Aging 20220929 18
There is considerable heterogeneity in the genomic drivers of lung adenocarcinoma, which has a dismal prognosis. Bioinformatics analysis was performed on lung adenocarcinoma (LUAD) datasets to establish a multi-autophagy gene model to predict patient prognosis. LUAD data were downloaded from The Cancer Genome Atlas (TCGA) database as a training set to construct a LUAD prognostic model. According to the risk score, a Kaplan-Meier cumulative curve was plotted to evaluate the prognostic value. Furt ...[more]
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