MXene catalytic amplification-fluorescence/absorption dimode aptamer sensor for the detection of trace Pb²⁺ in milk.

ABSTRACT: Lead ion (Pb²⁺) is a toxic heavy metal, which is very harmful to organisms. Therefore, the establishment of a rapid, simple, and sensitive method is of great significance to food safety and human health. It was found that MXeneTi₃C₂ nanosheet (NS) has a strong catalytic effect on the oxidation of 3,3,5,5-tetramethylbenzidine (TMB) via H₂O₂ to form the oxidized product (TMB_OX); it has a strong fluorescence peak at 415 nm and an absorption (Abs) peak at 295 nm. The aptamer of Pb²⁺ (Apt_pb) can be adsorbed on the surface of an NS to form MXene-Apt conjugates, which reduces its catalytic active sites and inhibits its catalytic activity. When the target Pb²⁺ is added, it specifically binds w

SUBMITTER: Zhi S 

PROVIDER: S-EPMC9622933 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature