Dataset Information

Individual glycemic responses to carbohydrates vary and reflect underlying metabolic physiology (Olink)

ABSTRACT: Proteomics data was measured by using the Olink Explore 1536 panel from baseline plasma sample. The project is also supported by Themistocles L Assimes (Stanford University tassimes@stanford.edu) and Fahim Abbasi (Stanford University, fahim@stanford.edu).

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Yue Wu

LAB HEAD: Michael Snyder

PROVIDER: PAD000001 | Pride | 2025-03-31

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	StanfordProject_FahimAbbasi_Analysis_Report_2022-09-22.pdf	Pdf
	checksum.txt	Txt
	olink_npx.csv	Csv

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Publications

Individual variations in glycemic responses to carbohydrates and underlying metabolic physiology.

Wu Yue Y Ehlert Ben B Metwally Ahmed A AA Perelman Dalia D Park Heyjun H Brooks Andrew Wallace AW Abbasi Fahim F Michael Basil B Celli Alessandra A Bejikian Caroline C Ayhan Ekrem E Lu Yingzhou Y Lancaster Samuel M SM Hornburg Daniel D Ramirez Lucia L Bogumil David D Pollock Sarah S Wong Frank F Bradley Denver D Gutjahr Georg G Rangan Ekanath Srihari ES Wang Tao T McGuire Lettie L Venkat Rangan P P Ræder Helge H Shipony Zohar Z Lipson Doron D McLaughlin Tracey T Snyder Michael P MP

Nature medicine 20250604 7

Elevated postprandial glycemic responses (PPGRs) are associated with type 2 diabetes and cardiovascular disease. PPGRs to the same foods have been shown to vary between individuals, but systematic characterization of the underlying physiologic and molecular basis is lacking. We measured PPGRs using continuous glucose monitoring in 55 well-phenotyped participants challenged with seven different standard carbohydrate meals administered in replicate. We also examined whether preloading a rice meal ...[more]

PMID: 40467897

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