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Proteomic analysis of Plasmodium yoelii salivary gland sprozoites

ABSTRACT: Proteomic analysis of Plasmodium yoelii salivary gland sprozoites

INSTRUMENT(S): LTQ Orbitrap Velos

ORGANISM(S): Plasmodium Yoelii Yoelii 17xnl

DISEASE(S): Malaria

SUBMITTER: Kristian Swearingen

LAB HEAD: Robert L. Moritz

PROVIDER: PXD009727 | Pride | 2019-10-02

REPOSITORIES: Pride

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Total and putative surface proteomics of malaria parasite salivary gland sporozoites.

Lindner Scott E SE Swearingen Kristian E KE Harupa Anke A Vaughan Ashley M AM Sinnis Photini P Moritz Robert L RL Kappe Stefan H I SH

Molecular & cellular proteomics : MCP 20130116 5

Malaria infections of mammals are initiated by the transmission of Plasmodium salivary gland sporozoites during an Anopheles mosquito vector bite. Sporozoites make their way through the skin and eventually to the liver, where they infect hepatocytes. Blocking this initial stage of infection is a promising malaria vaccine strategy. Therefore, comprehensively elucidating the protein composition of sporozoites will be invaluable in identifying novel targets for blocking infection. Previous efforts ...[more]

PMID: 23325771

Publication: 1/2

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