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Secretome Analysis of Mycobacterial-infected Bovine Macrophages

ABSTRACT: Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, a chronic granulomatous disease. Mtb is mostly restricted to humans and seldom causes disease in animals. M. bovis (Mbv) on the other hand causes tuberculosis in cows (bovine tuberculosis) and several wild animals. Each of these pathogens therefore has unique host adaptations and the host- and pathogen-specific factors driving this differential tropism still remain largely unknown. Here we profiled the secretomes of Mtb- and Mbv-infected bovine macrophages to characterise host-specific responses to each pathogen.

INSTRUMENT(S):

ORGANISM(S): Bos Taurus (bovine)

TISSUE(S): Macrophage

DISEASE(S): Tuberculosis

SUBMITTER: Matthias Trost

LAB HEAD: Matthias Trost

PROVIDER: PXD017949 | Pride | 2021-03-11

REPOSITORIES: Pride

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			Action	DRS
	20181130_TH_CQ_bMo_Mbv_D1.raw	Raw
	20181130_TH_CQ_bMo_Mbv_D2.raw	Raw
	20181130_TH_CQ_bMo_Mbv_D3.raw	Raw
	20181130_TH_CQ_bMo_Mtb_D1.raw	Raw
	20181130_TH_CQ_bMo_Mtb_D2.raw	Raw

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