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MS-based proteomic characterization of Toxoplasma gondii SNF2L, SNF2h, RFTS and RSF1d interactomes

ABSTRACT: In eukaryotic cells, ATP-dependent chromatin remodelers are specialized multiprotein machines that organize the genome and rule its accessibility by repositioning, ejecting or modifying nucleosomes, but their role in Toxoplasma gondii is still poorly understood. Phylogenetic analyzes show that the parasite retains the commonly recognized remodeler families and has evolved two divergent proteins within the ISWI family: TgSNF2h and TgSNF2L. To gain insight into the role played by these structurally divergent proteins, we characterized their interactomes and those of two associated partners, RFTS and RSF1d.

INSTRUMENT(S): LTQ Orbitrap Velos, Orbitrap Ascend, Q Exactive HF, Q Exactive

ORGANISM(S): Homo Sapiens (human) Toxoplasma Gondii Rh

SUBMITTER: Yohann Couté

LAB HEAD: Yohann Couté

PROVIDER: PXD056911 | Pride | 2025-02-19

REPOSITORIES: Pride

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			Action	DRS
	TgRFTS-global_R1.mgf	Mgf
	TgRFTS-global_R1.raw	Raw
	TgRFTS-global_R2.mgf	Mgf
	TgRFTS-global_R2.raw	Raw
	TgRFTS-global_R3.mgf	Mgf

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