Mass spectrometry analysis of proteins interacting with Fbxw7 in T cells

ABSTRACT: To elucidate how gut microbiota (GM) downregulated Fbxw7, we treated CD4+ T cells with GM-lysates and pulled down Fbxw7 in the cell lysates. Then, the precipitated proteins were analyzed by mass spectrometry, and eight E3 ligases were revealed to interact with Fbxw7.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): T Cell, Cell Culture

SUBMITTER: peihan wu  

LAB HEAD: Zhijian Cai

PROVIDER: PXD057140 | Pride | 2025-04-16

REPOSITORIES: Pride