Age-related changes in the proteome and mitochondrial metabolism of rabbit adipose-derived stromal/stem cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Oryctolagus Cuniculus (rabbit)
TISSUE(S): Adipose-derived Stromal Cell, Mesenchymal Stem Cell Of Adipose
SUBMITTER: 
Alicia Toto Nienguesso
LAB HEAD: Anne Navarrete Santos
PROVIDER: PXD057467 | Pride | 2025-01-19
REPOSITORIES: Pride
Dataset's files
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Publications
Age-related changes in the proteome and mitochondrial metabolism of rabbit adipose-derived stromal/stem cells.
Toto Nienguesso Alicia A Jung Juliane-Susanne JS Alfes Marie M Schindler Maria M Täubert Luisa L Schmidt Carla C Navarrete Santos Anne A
Scientific reports 20250620 1
Adipose tissue is continuously regenerated by stromal mesenchymal stem cells throughout life. This study hypothesises that early age-related changes in the proteome and metabolic properties of subcutaneous (s) and visceral (v) adipose tissue-derived stromal/stem cells (ASCs) from young and old rabbits contribute to a loss of stem cell plasticity and function. To test this, the proteome and metabolic properties of ASCs from young and old rabbits were analysed using mass spectrometry-based label-f ...[more]
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