Dataset Information
Peptidomics of sorted TPH1 positive cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Type Ec Enteroendocrine Cell, Small Intestine
DISEASE(S): Type 2 Diabetes Mellitus
SUBMITTER: 
Richard Kay
LAB HEAD: Frank Reimann
PROVIDER: PXD062039 | Pride | 2025-11-03
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 22090201.mgf | Mgf | |||
| 22090201.raw | Raw | |||
| 22090202.mgf | Mgf | |||
| 22090202.raw | Raw | |||
| 22090203.mgf | Mgf |
Items per page: 1 - 5 of 22 |
Publications
Mechanisms of Activation and Serotonin Release From Human Enterochromaffin Cells.
Cellular and molecular gastroenterology and hepatology 20250813 12
<h4>Background & aims</h4>Gastrointestinal (GI) enterochromaffin (EC) cells are specialised sensors of luminal stimuli. They secrete most of the body's serotonin (5-HT), and are critical for modulating GI motility, secretion, and sensation, while also signaling satiety and intestinal discomfort. The aim of this study was to investigate mechanisms underlying the regulation of human EC cells, and the relative importance of direct nutrient stimulation compared with neuronal and paracrine regulation ...[more]
