Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

SH2D1A Facilitates the Progression of T-Cell Acute Lymphoblastic Leukemia

ABSTRACT: SH2D1A Facilitates the Progression of T-Cell Acute Lymphoblastic Leukemia

PROVIDER: PRJNA1192715 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR31563940_1.fastq.gz	Fastqsanger.gz
	SRR31563940_2.fastq.gz	Fastqsanger.gz
	SRR31563941_1.fastq.gz	Fastqsanger.gz
	SRR31563941_2.fastq.gz	Fastqsanger.gz
	SRR31563942_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

SH2D1A Facilitates the Progression of T-Cell Acute Lymphoblastic Leukemia

Project description:T-cell acute lymphoblastic leukemia (T-ALL) is a highly aggressive hematologic malignancy. The potential of investigating SH2D1A holds promise for more targeted therapies and better outcomes. Knocking down SH2D1A led to decreased T-ALL cell survival and growth both in vitro and in vivo. Cleavage Under Targets and Tagmentation (CUT&Tag) showed the occupancy of ETS1 and RUNX1 at the enhancer loci of SH2D1A in 6T-CEM cells.

2025-04-21 | GSE283240 | GEO

SH2D1A Promotes CHI3L2 Expression and Facilitates the Progression of T-Cell Acute Lymphoblastic Leukemia

Project description:T-cell acute lymphoblastic leukemia (T-ALL) is a highly aggressive hematologic malignancy. The potential of investigating SH2D1A holds promise for more targeted therapies and better outcomes. Knocking down SH2D1A led to decreased T-ALL cell survival and growth both in vitro and in vivo. RNA-seq analysis was conducted and the differently expressed genes were revealed in the SH2D1A-knockdown Jurkat and 6T-CEM cells in comparison to control group.

2025-04-21 | GSE283165 | GEO

SH2D1A Promotes CHI3L2 Expression and Facilitates the Progression of T-Cell Acute Lymphoblastic Leukemia

Project description:SH2D1A Promotes CHI3L2 Expression and Facilitates the Progression of T-Cell Acute Lymphoblastic Leukemia

| PRJNA1192263 | ENA

SOX4 promotes T cell acute lymphoblastic leukemia progression

Project description:SOX4 promotes T cell acute lymphoblastic leukemia progression

| PRJNA1052077 | ENA

Proteogenomics of High hyperdiploid childhood acute lymphoblastic leukemia

Project description:Proteogenomic analysis and genomic profiling, RNA-sequencing, and mass spectrometry-based analysis of High hyperdiploid childhood acute lymphoblastic leukemia.

2020-01-29 | MSV000084862 | MassIVE

Proteogenomics of High hyperdiploid childhood acute lymphoblastic leukemia

Project description:Proteogenomic analysis and genomic profiling, RNA-sequencing, and mass spectrometry-based analysis of High hyperdiploid childhood acute lymphoblastic leukemia.

2019-02-25 | PXD010175 | Pride

SOX4 promotes T cell acute lymphoblastic leukemia progression

Project description:We report a previously unrecognized role of SOX4 in T cell acute lymphoblastic leukemia (T-ALL). To explore SOX4-dependent gene regulation, RNA-seq analysis was conducted and the differently expressed genes were revealed in the SOX4-knockdown Jurkat cells in comparison to control group.

2024-12-31 | GSE250129 | GEO

MicroRNA-sequencing of Brazilian pediatric acute lymphoblastic leukemia

Project description:MicroRNA-sequencing of the bone marrow samples from Brazilian pediatric patients with B-cell acute lymphoblastic leukemia (B-ALL) and T-cell acute lymphoblastic leukemia (T-ALL).

2022-04-13 | E-MTAB-11621 | biostudies-arrayexpress

The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution

Project description:The bone marrow microenvironment of leukemia plays a key role in leukemia progression, but its molecular complexity in pre-B acute lymphoblastic leukemia (B-ALL), the most common cancer in children, remains poorly understood. Here we use single-cell RNA sequencing to characterise the bone marrow microenvironment during B-ALL progression.

2020-07-27 | GSE148115 | GEO

MicroRNA expression profiles in acute lymphoblastic leukemia

Project description:MicroRNA in acute lymphoblastic leukemia

| PRJEB51832 | ENA